Croscarmellose Sodium (India)

APPLICATIONS :

Croscarmellose sodium is used in oral pharmaceutical formulations as a disintegrant for Capsules, Tablets and Granules.



In tablet formulations, Croscarmellose sodium may be used in both direct-compression and wet-granulation processes.



When used in wet granulations the Croscarmellose sodium is best added in both the wet and dry stages of the process (intra- and extra granularly) so that the wicking and swelling ability of the disintegrant is best utilized.



Concentrations of up to 5 w/w of Croscarmellose sodium may be used as a tablet disintegrant although normally 2 w/w is used in tablets prepared by direct compression and 3 w/w in tablets prepared by a wet-granulation process.