Propranolol HCL (India)

NOMENCLATURE

: (2 RS)-1-[(1-Methyllethyl) amino ] -3-

(Naphthalen – 1- Yloxy) Propan –2ol Hydrochloride.



: (RS) –1- Isopropylamino-3-(1- Naphthyloxy) Propan – 2 ol Hydrochloride.





CAS NO.

: 318-98-9





EMPIRICAL FORMULA

:C16H21NO2.HCL.





MOL. WT.

: 295.8





MELTINGN POINT

: 162°C TO 165°C



DESCRIPTION

: A White or almost white powder, Soluble in Water and in Alcohol.





APPLICATIONS

: Beta-Adrenoceptor antagonist.



SPECIFIC ROTATION

:Between -1.0° and +1.0°





7.ACIDITY OR ALKALINITY(PH)

: Confirms BP requirements.

(PH = 5.0 to 6.0, in 1.0 Solution).





RESIDUE ON IGNITION (Sulphated Ash)

:NMT 0.1 .





LOSS ON DRYING

:NMT 0.5 .





HEAVY METALS

: NMT 20 ppm.





ORGANIC VOLATILE IMPURITIES

:Meets the requirements as per USP.





ASSAY (By Potentiometrically)

: 99 to 101 .