Mebendazole (India)

1. NOMENCLATURE : Methyl (5-Benzoyl-1H-Benzimidazol-

2-yl)Carbam

: Methyl N-(5-benzoyl-1H-benzimida

2-yl)carbamate,

: Methyl N-(5-benzoyl-2-

benzimidazolyl) carbamate



2. CAS NO. : 31431 – 39 – 7





3. EMPIRICAL FORMULA : C16H13N3O3





4. MOL. WT. : 295.30



5. MELTING RANGE : 290°C



6. DESCRIPTION : Off - white powder.

Slight characteristic odour.



7. THERAPEUTIC USE : Anthelm

: It is used to treat inspections caused

by worms such as whipworm,

pinworm, roundworm, and hookworm

in humans and animals.





8. SOLUBILITY : Practically Insoluble in water,

Alcohol and in Methylene Chlori

: Freely Soluble in Formic Acid.



9. MELTING POINT : 290°C





10. LOSS ON DRYING : NMT 0.5





11. HEAVY METALS : NMT 20 ppm. (0.002 )





12. RESIDUE ON IGNITION: NMT 0.1

(Sulphated Ash)





13. ORGANIC VOLATILE : As per U.S.P.

IMPURITIES (OVI)





14. RELATED SUBSTANCES: Single impurity : NMT 0.5

(By TLC) Total impurities : NMT 1.0



15. ASSAY (Purity) : Between 98.0 - 102





16. PACKING : 20 Kgs. / 25 Kgs., HDPE / Fibre Drums

with double PE Liners.



17. STORAGE : Store in wll –closed, light –resistant

containers. (Protected from light)