Ibuprofen (India)

1. NOMENCLATURE : (2 RS) – 2- [4- (2-Methyl Propyl)

Phenyl] Propionic Acid.

: 2-(4-Iso Butyl Phenyl) Propionic Acid.

: P- Iso Butyl Hydratropic Acid.



2. CAS NO. : 15687-27-1



3. EMPIRICAL FORMULA : C13H18O2



4.DESCRIPTION : White crystalline powder,

(Free flowing), with characteristic order.



5.THERAPEUTIC USE : Anti-Inflammatory & Analgesic



6.SOLUBILITY : Practically insoluble in Water

: Freely soluble in Acetone, in Methanol

and in Methylene Chloride.

: It dissolves in Dilute solutions of Alkali

Hydroxides and Carbonates.





7. MOL. WT. : 206.30



8. MELTING POINT : 75°C – 78°C



9. IMPUTIRY F : Maximum 0.1 BY GAS CHROMATOGRAPHY





10 . CLARITY & COLOUR OF : 10 Solution in Methanol is

SOULTION Clear and Colorless

(APPEARANCE OF SOLUTION)





11.OPTICAL ROTATION : -0.05° to +0.05°





12.HEAVY METALS : Not more than 10 ppm.





13. LOSS ON DRYING : Not more than 0.5





14. SULPHATED ASH : Not more than 0.1





15. ASSAY (ODB) : 98.5 to 101